PREPTOWER-Chromatography Separation System

We want to introduce an ECOM product news – the PREPTOWER – a complete flash or preparative modular system with an excellent price-performance ratio. This system is designed for maximum flexibility and allows scaling from small test separations to large-scale production. 

Applications

This system finds applications in many industrial and scientific fields such as:

• Pharmaceutical purification of natural extracts - separation of cannabinoids (CBD, CBN, CBG, CBC, THC), peptides, oligonucleotides, algae extracts, or oleoresins.
• Centrifugal liquid chromatography (CCC/CPC) - purification of complex mixtures using liquid phase separation
• New molecule development and synthesis - the system allows for both small-scale testing and scaling up to pilot and production levels.

Technical specifications

Three pumps for optimal performance:

• Two main pumps enable a "high-pressure gradient" with parallel interconnection of pumps.
• One pump has a built-in 6-way valve for solvent selection, expanding separation options.
• A third optional pump is designed for repetitive sampling of large-volume samples.

Injection and switching valves
The instrument is equipped with a loop injection valve for efficient sample dispensing.
The switching valve allows CCC/CPC separations in both upflow and downflow modes.
The unit contains switching valves: VOI6SCS0 and VOI4SCS0 and manifold valves: VOS6PES0 (in PrepTower 1000 and 500) and VOS1EDS0 (in PrepTower 300).

Advanced PDA detector
The system includes a universal PDA detector that measures absorbance at up to four wavelengths simultaneously.
The maximum detection range reaches 800 nm, allowing work with a wide range of substances.

Software and user interface
ECOMAC or Clarity Software
The system is controlled via the internally installed ECOMAC or Clarity software, which meets FDA 21 CFR Part 11 standards.
An intuitive user interface allows for easy method setup and real-time process monitoring

Modularity and scalability

• Full customization for specific applications
• The system can be easily adapted to your specific needs, whether you are working with small lab samples or performing high throughput production separations.
• A working range of flow rates from 10 ml/min up to 6000 ml/min allows automatic switching between different scales without the need for a complex setup.

The flow cell: By default the flow cell 3HP08000 with adjustable optical path (0.058 mm – 5 mm) is included.

Customization: If necessary the unit is customizable to customer application needs in terms the scale – from small flash sample separation testing through pilot scale prediction to high-capacity production.
It could work in ranges of 10 ml/min. – 6000 ml/min and it can be easily and automatically switched between these scales.